Brain Tumors and Oncology​

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As an adjunct to traditional brain tumor surgical resection and/or decompression, new technologies may be applied, such as Laser Interstitial Thermal Therapy (LITT), to first biopsy and ablate brain tumors. LITT is a procedure that involves a small bone opening and insertion of the laser probe into a specified target, typically performed with the patient asleep under general anesthesia in the MRI scanner. Rather than surgically removing a tumor, LITT can destroy it using heat generated by a laser at the tip of a very thin probe. This minimally invasive procedure is performed through an incision about the width of a pencil's eraser, and most patients are discharged home within 1 day.

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Preclinical and research studies are underway to develop new drug delivery methods for brain tumors. One approach uses convection-enhanced delivery with pressure, but also a novel methodology using electrokinetic transport (termed electrokinetic convection-enhanced delivery, ECED), which Dr. Faraji pioneered and has published on. ECED is currently being evaluated on research models to determine safety and efficacy prior to human clinical trials. This work is being conducted in the Clinical Innovations Laboratory at the Houston Methodist Research Institute.

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